Product Overview
Applications
Flow Cyt, ICC/IF, WB
Reactivity
Mouse, Rat, Dog, Human, African green monkey
Target Information
Alternative Names
18 kDa phosphoprotein; CFL 1; CFL; CFL1; COF1_HUMAN; Cofilin 1; Cofilin 1 non muscle; Cofilin; Cofilin non muscle isoform; Cofilin-1; epididymis secretory protein Li 15; HEL-S-15; non-muscle isoform; p18
Tissue Specificity
Widely distributed in various tissues.
Function
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Upon delivery aliquot and store at -20 °C. Avoid freeze / thaw cycles.
Storage Buffer
PBS, 50% Glycerol, 0.1% BSAPBS (without Mg2+ and Ca2+), BSA (IgG, protease free). pH: 7.3.
Preservative
0.05% Sodium Azide
