CMA (Cridanimod), STING Agonist

Inquiry

Cat. No.

CLIA-0130234

Product Size

5 mg 25 mg Custom Size

Product Overview

Description

murine-selective STING agonist.

Purity

> 98%

Form

Solid

Alternative Names

Cridanimod

Target

STING

Biological Description

CMA (Cridanimod) is a murine-selective STING agonist (Kd = 3.5 μM). It directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. CMA triggers type I IFN response in murine macrophages. However, does not activate human STING signaling.

CAS Number

38609-97-1

Solubility Overview

Soluble in DMSO to > 75 mM.

Chemical Properties

Chemical Name

2-(9-oxoacridin-10-yl)acetic acid

Molecular Weight (Da)

253.25

Molecular Formula

C₁₅H₁₁NO₃

PubChem Identifier

38072

SMILES

C1=CC=C2C(=C1)C(=O)C3=CC=CC=C3N2CC(=O)O

Storage & Handling

Storage Instructions

Shipped at 4 °C. Store at -20 °C.

For Research Use Only. Not For Clinical Use.