Product Size
25 mg
10 mg
Custom Size
Product Overview
Description
Nucleoside analogue that induces DNA double-strand breaks. Adenosine deaminase inhibitor.
Target
Adenosine deaminase
Biological Description
Nucleoside analogue that induces DNA double-strand breaks. Adenosine deaminase inhibitor. Active in vivo and in vitro. Orally active.
Solubility Overview
Soluble in DMSO to 100 mM.
Chemical Properties
Chemical Name
(2R,3S,5R)-5-(6-Amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
Molecular Weight (Da)
285.69
Molecular Formula
C10H12ClN5O3
SMILES
C1C(C(OC1N2C=NC3=C2N=C(N=C3N)Cl)CO)O
Storage & Handling
Storage Instructions
Store at room temperature. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
