Product Size
5 mg
1 mg
Custom Size
Product Overview
Description
Antibiotic agent. Phytotoxin.
Biological Description
Antibiotic agent. Phytotoxin. Cytochalasin analog. Targets filamentous actin and induces apoptosis. Shows cytotoxic effects against cancer cell lines. Shows antibacterial and nematicidal effects. Induces tissue necrosis in vivo.
Solubility Overview
Soluble in DMSO to 10 mM.
Chemical Properties
Chemical Name
(7S,13E,16S,17E,19R,21E)-6,7-Epoxy-19-hydroxy-10-(1H-indol-3-yl)-16,18-dimethyl- [13]cytochalasa-13,17,21-triene-1,20,23-trione
Molecular Weight (Da)
528.64
Molecular Formula
C32H36N2O5
SMILES
C[C@H]\1C/C=C/[C@H]2[C@H]3[C@](O3)([C@H]([C@@H]4[C@@]2(C(=O)/C=C/C(=O)[C@@H](/C(=C1)/C)O)C(=O)N[C@H]4CC5=CNC6=CC=CC=C65)C)C
Storage & Handling
Storage Instructions
Store at -20 °C. It is important to note that this product is reported to be light sensitive. Store in the dark. Store under desiccating conditions.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
