Product Size
50 mg
10 mg
Custom Size
Product Overview
Description
Positive GABAB receptor allosteric modulator.
Biological Description
Positive GABAB receptor allosteric modulator (EC50 values are 5.37 and 4.60 μM, respectively). Increases receptor agonist affinity and signal transduction efficacy. Also shown to potentiate receptor response to baclofen.
Solubility Overview
Soluble in DMSO to 100 mM and in ethanol to 100 mM.
Chemical Properties
Chemical Name
3,5-Bis(1,1-dimethylethyl)-4-hydroxy-β,β-dimethylbenzenepropanol
Molecular Weight (Da)
292.46
Molecular Formula
C19H32O2
SMILES
CC(C)(C)c1cc(cc(c1O)C(C)(C)C)CC(C)(C)CO
Storage & Handling
Storage Instructions
Store at room temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
