Product Overview
Reactivity
Human, Mouse, Monkey
Applications
IF, IHC, Peptide-ELISA, WB
Target Information
Alternative Names
CEP72; Centrosomal protein 72kDa; Centrosomal protein of 72 kDa; KIAA1519
Function
Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes. Involved in centriole duplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Upon receipt, store at -20 °C. Avoid freeze-thaw cycles.