CEP63 Rabbit Polyclonal Antibody

Cat. No.: CLAB-00230587

Product Size: 20 µL 100 µL Custom Size

Product Overview

Isotype
IgG
Reactivity
Human
Clonality
Polyclonal
Host Species
Rabbit
Conjugation
Unconjugated
Applications
Peptide-ELISA, WB

Target Information

Target Name
CEP63
UniProt No.
Gene ID
Alternative Names
CEP63; Centrosomal protein of 63 kDa; Centrosome protein CEP63; Centrosomal protein 63kDa
Function
Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks , is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Upon receipt, store at -20 °C. Avoid freeze-thaw cycles.

For Research Use Only. Not For Clinical Use.

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