CEP63 Rabbit Polyclonal Antibody (aa520-548)

Cat. No.: CLAB-00230606

Product Size: 20 µL 100 µL Custom Size

Product Overview

Isotype
IgG
Reactivity
Human
Clonality
Polyclonal
Host Species
Rabbit
Conjugation
PE
Applications
ELISA, IHC, WB

Target Information

Target Name
CEP63
UniProt No.
Gene ID
Alternative Names
CEP63; Centrosomal protein of 63 kDa; Centrosome protein CEP63; Centrosomal protein 63kDa
Function
Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks , is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Short term: store at 4 °C. Long term: aliquot and store at -20 °C for up to 6 months. Avoid freeze-thaw cycles. Protect from light.

For Research Use Only. Not For Clinical Use.

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