CEP63 Mouse Monoclonal Antibody (OTI2H8)

Cat. No.: CLAB-00230579

Product Size: 20 µL 100 µL Custom Size

Product Overview

Isotype
IgG1
Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Conjugation
Unconjugated
Applications
WB

Target Information

Target Name
CEP63
UniProt No.
Gene ID
Alternative Names
CEP63; Centrosomal protein of 63 kDa; Centrosome protein CEP63; Centrosomal protein 63kDa
Function
Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks , is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Store at -20 °C. Avoid freeze-thaw cycles.

For Research Use Only. Not For Clinical Use.

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