Product Overview
Reactivity
Human, Mouse, Canine
Applications
ICC/IF, IP, WB, KD
Target Information
Alternative Names
CAP350GM133; Centrosomal protein 350kDa; centrosome-associated protein 350; Centrosome-associated protein of 350 kDa; Cep350; FLJ38282; FLJ44058; KIAA0480centrosome associated protein 350
Function
Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity. Required for ciliation.
Tissue Specificity
Detected in heart, brain, skeletal muscle, testis, placenta, lung, liver, kidney and pancreas.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Store at 4 °C. Do not freeze.
Storage Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0).
Preservative
0.09% Sodium Azide
