Product Overview
Target Information
Alternative Names
CEP350; CAP350; GM133; KIAA0480; Centrosomal protein 350kDa
Function
Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity. Required for ciliation.
Tissue Specificity
Detected in heart, brain, skeletal muscle, testis, placenta, lung, liver, kidney and pancreas.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Store at -20 °C. Avoid freeze-thaw cycles.