Product Overview
Target Information
Alternative Names
CEP19; C3orf34; Centrosomal protein of 19 kDa; Centrosomal protein 19kDa
Function
Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule anchoring to the centrosomes.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Upon receipt, store at -20 °C or -80 °C. Avoid repeated freeze.
