CEP164 Rabbit Polyclonal Antibody

Cat. No.: CLAB-00230369

Product Size: 20 µL 100 µL Custom Size

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Product Overview

Isotype

IgG

Reactivity

Dog, Rat, Human

Clonality

Polyclonal

Host Species

Rabbit

Conjugation

Unconjugated

Applications

IHC, Peptide-ELISA, WB

Target Information

Target Name

CEP164

UniProt No.

Q9UPV0

Gene ID

22897

Alternative Names

CEP164; Centrosomal protein of 164 kDa; Centrosomal protein 164kDa; KIAA1052; NPHP15

Function

Plays a role in microtubule organization and/or maintenance for the formation of primary cilia , a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA, CHEK2 and CHEK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHEK1.

Tissue Specificity

Expressed in several cell lines.

Shipping & Handling

Shipping

Shipped on dry ice.

Storage

Upon receipt, store at -20 °C. Avoid freeze-thaw cycles.

For Research Use Only. Not For Clinical Use.