CEP164 Rabbit Polyclonal Antibody (aa246-274)

Cat. No.: CLAB-00230379

Product Size: 20 µL 100 µL Custom Size

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Product Overview

Isotype

IgG

Reactivity

Human

Clonality

Polyclonal

Host Species

Rabbit

Conjugation

Applications

ELISA, Flow Cyt, WB

Target Information

Target Name

CEP164

UniProt No.

Q9UPV0

Gene ID

22897

Alternative Names

CEP164; Centrosomal protein of 164 kDa; Centrosomal protein 164kDa; KIAA1052; NPHP15

Function

Plays a role in microtubule organization and/or maintenance for the formation of primary cilia , a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA, CHEK2 and CHEK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHEK1.

Tissue Specificity

Expressed in several cell lines.

Shipping & Handling

Shipping

Shipped on dry ice.

Storage

Short term: store at 4 °C. Long term: aliquot and store at -20 °C for up to 6 months. Avoid freeze-thaw cycles. Protect from light.

For Research Use Only. Not For Clinical Use.