CEP135 Rabbit Polyclonal Antibody (aa93-142)

Cat. No.: CLAB-00230342

Product Size: 20 µL 100 µL Custom Size

Product Overview

Reactivity
Human, Monkey, Chimpanzee, Orangutan, Gibbon
Clonality
Polyclonal
Host Species
Rabbit
Conjugation
Biotin
Applications
WB

Target Information

Target Name
CEP135
UniProt No.
Gene ID
Alternative Names
CEP135; Centrosomal protein of 135 kDa; CEP4; Centrosomal protein 4; Centrosome protein cep135; Centrosomal protein 135kDa; KIAA0635; MCPH8
Function
Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP and CEP290 and recruitment of WRAP73 to centrioles. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole. Required for the recruitment of CEP295 to the proximal end of new-born centrioles at the centriolar microtubule wall during early S phase in a PLK4-dependent manner.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Short term: store at 4 °C. Long term: add glycerol to 40-50%, aliquot to avoid freeze-thaw cycles, and store at -20 °C. Protect from light.

For Research Use Only. Not For Clinical Use.

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