CEP135 Rabbit Polyclonal Antibody (aa1000-1050)

Cat. No.: CLAB-00230338

Product Size: 20 µL 100 µL Custom Size

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Product Overview

Isotype

IgG

Reactivity

Human

Clonality

Polyclonal

Host Species

Rabbit

Conjugation

Unconjugated

Applications

Target Information

Target Name

CEP135

UniProt No.

Q66GS9

Gene ID

9662

Alternative Names

CEP135; Centrosomal protein of 135 kDa; CEP4; Centrosomal protein 4; Centrosome protein cep135; Centrosomal protein 135kDa; KIAA0635; MCPH8

Function

Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP and CEP290 and recruitment of WRAP73 to centrioles. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole. Required for the recruitment of CEP295 to the proximal end of new-born centrioles at the centriolar microtubule wall during early S phase in a PLK4-dependent manner.

Shipping & Handling

Shipping

Shipped on dry ice.

Storage

Store at 2-8 °C for up to one year.

For Research Use Only. Not For Clinical Use.