Centrosome pAb Development Service

Inquiry

Centrosome is considered as the potential target of therapy and diagnosis of cancer and many other related diseases. Polyclonal antibodies (pAbs) are powerful tools in the fields of research and medicine. CD BioSciences provides centrosome pAbs development service with our advanced technology and experienced experts for meeting our global customer's demands in centrosome research and the therapeutic development of centrosome-related disease.

Antibody

Overview of Centrosome Antibodies

Hundreds of proteins are localized in human centrosome, which make up to 3% of protein encoding genes. The centrosomes are of important functions in many biological processes, including cell division, cell migration and others. However, the size, components, abundance and localization of centrosomal proteins vary from cells, which are highly associated with their tissue-specific functions. Therefore, anti-centrosome polyclonal antibodies are very powerful tools for understanding the biogenesis and functions of these enigmatic structures.

What's more, many of the centrosomal proteins are involved in a variety of mechanisms that cause disorders and diseases, such as ciliopathic diseases, carcinogenesis, neurogenesis, and other diseases such as dwarfisms and microcephaly. And multiple cancer-associated proteins are located or trafficked in and out of centrosomes. In clinical uses, pAbs are used in many diagnostic tests and cancer therapy due to their ability to multi-target tumor cells compared to mAbs. Following is the comparison between hosts for polyclonal antibody development.

Animal Advantage Disadvantage
Chicken
  • Non-mammalian host species
  • Difficult to isolate antibodies from yolks
  • Not ideal for peptide projects
  • Good alternative for highly conserved mammalian proteins
  • Non-invasive (antibodies are purified from egg yolks)
Sheep/Goat
  • Large mammalian host species
  • Not ideal for modified peptides
  • Larger antigen quantities
  • High quantity (250mL) sera for large lots
  • Serum can be used directly in initial assays
Llama/Camel
  • Large mammalian host species
  • Not ideal for small molecule or peptide antigens
  • Heavy-chain only antibodies
  • Serum can be used directly
Rabbit
  • Most common host species
  • Not ideal for highly conserved mammalian proteins

Our Services

CD BioSciences is committed to providing scientific research institutions and pharmaceutical companies with one-stop custom antibody services. With years of experience in antibody development and production and advanced technology, our professional scientists are willingly to devote themselves for assisting you making better progress in your research. Our centrosome antibody development services include but not limited as follows.

Rabbit pAb Service

Rabbit pAb Service

Chicken pAb Service

Chicken pAb Service

Llama/Camel pAb Service

Llama/Camel pAb Service

Sheep/Goat pAb Service

Sheep/Goat pAb Service

Workflow of Our Service

Our polyclonal antibody development services are based on years of process optimization and a strong reputation for reliable antibody production. We have been a preferred partner to various pharmaceutical companies worldwide for antibody development and production. Our workflow is as follows.

Workflow

Applications of Anti-centrosome Polyclonal Antibodies

  • Centrosomal gene functional study
  • Centrosomal protein localization and detection
  • Centrosome structural and numeric detection
  • Diagnosis and therapeutic development of centrosome-related disease

Why Choose Us

Professional Team

Professional Team

Comprehensive Platform

Comprehensive Platform

High Efficiency

High Efficiency

One-stop Service

One-stop Service

With skilled and experienced genomics and cytology experts, state-of-the-art equipment and advanced technology, CD BioSciences offers customer all over the word services related to fields of centrosomal research. Our one-stop service program is your best assistant to accelerate you process of centrosomal research. Please feel free to contact us and get started with our high-quality services.

Our services are for research use only and not for any clinical use.