Centrosomal Protein Imaging Service

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The functions of centrosome rely on the localization and enrichment of the centrosomal proteins. Protein imaging technology provides the localization, composition and interaction information of centrosomal proteins. CD BioSciences offers high-quality and professional centrosomal protein imaging service for research use. With advanced technology, equipment, and experienced scientists, we have assisted our global customers in the field of centrosome research.

Cell imaging

Introduction into Centrosomal Protein Imaging

Centrosomal proteins interact as networks in space and time in cells. The quantity and the composition of centrosomal proteins various along with the cell types and cell cycle. During cell division, the centrosome is the key responsible organelle for the correct formation and orientation of the mitotic spindle, ensuring proper segregation of sister chromatids to each of the daughter cells. Centrosomal proteins are widely used to annotating the location of centrosomes. What's more, by knowing where a protein localizes in cells, researchers are one step closer to understanding a protein's function. Centrosomal proteins are localized in particular site in cells to perform their functions. Enrichment of the centrosome proteins indicates the biological processes related to intracellular organization and transport, organization of microtubules, cell cycle progression and cell division.

Multi-target protein imaging of single cellMulti-target protein imaging of single cell (Klevanski M, et al. 2020)

The immunofluorescent is the technology used for light microscopy with a fluorescence microscope, which utilizes the specific binding between antibodies and their antigen for targeting the fluorescent dyes to specific biomolecule within a cell. It's frequently used in detecting the protein expression, subcellular localization and co-localizing of proteins. The immunofluorescent can tell the target centrosomal proteins' localization, quantity and other information directly and accurately.

The Applications of Centrosomal Protein Imaging

  • Protein subcellular localization
  • Functional study of centrosome
  • Cell cycle detection
  • Cell skeleton analysis
  • Cancer research
  • Chromosome abnormality research

Our Service

With the rich experience, advanced technology and high-quality products, CD BioSciences provides centrosomal protein imaging service of high resolution and multiple labels. The workflow is as follows.

Workflow

The Technologies of Our Services

With the advanced equipment and experienced experts, CD BioSciences offers protein imaging services with technologies including but not limited as follows.

  • Transmission Electron Microscope, TEM
  • Cryo-Electron Microscope, cryo-EM
  • Reflection Electron Microscope, REM
  • Scanning Electron Microscope, SEM
  • Nuclear Magnetic Resonance, NMR
  • Stochastic Optical Reconstruction Microscopy, STORM

Why Choose Us

Professional Team

Professional Team

Comprehensive Platform

Comprehensive Platform

High Efficiency

High Efficiency

One-stop Service

One-stop Service

With skilled and experienced genomics and cytology experts, state-of-the-art equipment and advanced technology, CD BioSciences offers customer all over the word services related to fields of centrosomal research. Our one-stop service program is your best assistant to accelerate you process of centrosomal research. Please feel free to contact us and get started with our high-quality services.

Reference

  1. Klevanski, M., Herrmannsdoerfer, F., Sass, S. et al. Automated highly multiplexed super-resolution imaging of protein nano-architecture in cells and tissues. Nat Commun 11, 1552 (2020).

Our services are for research use only and not for any clinical use.