Centrosomal Protein Expression Service
InquiryCentrosomal proteins play very important role in its functions and structure. They are considered as potential target for solid tumors. It's necessary to obtain centrosomal proteins for various downstream applications, such as therapeutic development. CD BioSciences offers high-quality and professional centrosomal protein expression service in various protein expression system for research use. With advanced technology, equipment, and experienced scientists, we have assisted our global customers in the field of centrosome research.
Introduction into Centrosomal Protein
Centrosomal proteins are involved in centrosome activities by serving as structural protein, enzymes and other functions. There are more than 450 types of proteins that have been reported to be expressed in human centrosome. The complex functions of centrosome rely on the diverse centrosomal proteins, as well as its duplication. The centrosome abnormality (CA), including abnormal centrosome number, excess PCM, defects in centrosome maturation and microtubule-nucleating capacity, and centrosome misorientation, are frequently observed in malignant tumors. Additionally, the extent of CA is associated with the progression of malignant tumors.
Protein expression strategy
In pre-malignant conditions, CA can also be observed. Multiple cancer-related proteins are located in centrosome including cell cycle-regulated proteins, oncogenes, tumor suppressors, ubiquitination and degradation-related proteins, DNA damage checkpoint proteins and many other proteins.
Therefore, centrosomal proteins are potential therapeutic targets for solid tumors. With a robust expression system, researchers can obtain the target proteins with high quality to study the structure and function of centrosomal proteins.
Our Service
To obtain stable centrosomal protein for various downstream applications, such as centrosome functional study, centrosome structural study, development of antibodies, therapeutical development and drug discovery, it's indispensable to generate a robust, efficient and reliable expression system of centrosomal protein expression. CD BioSciences provides protein expression services in systems including but not limited as follows.
| Expression System | Advantages |
|---|---|
| Algae Expression System | Photosynthetic system Optimized system for robust selection and expression Cost-effective Simple culture conditions Endotoxin-free |
| Non-cell Expression System | Open system Able to add unnatural components Fast expression Simple format Easy for purification |
Bacteria Expression System
|
Scalable Cost-effective Simple culture conditions High-throughput capability Fast expression |
Yeast Expression System
|
Eukaryotic protein expression processing Scalable up to fermentation Simple media requirements High-level expression Endotoxin-free |
Insect Expression System
|
Similar to mammalian protein processing Able to grow on static or suspension culture Efficient and proper protein folding and post-translational modification Able to produce large proteins |
Mammalian Cell Expression System
|
Well-characterized genetic background High-level protein processing Produce protein transiently or stably Robust optimized system Efficient and proper protein folding and post-translational modification Able to produce large proteins |
| Plant Expression System | Easy to scale-up Complex post-translational modifications Endotoxin-free |
Why Choose Us
Professional Team
Comprehensive Platform
High Efficiency
One-stop Service
With skilled and experienced genomics and cytology experts, state-of-the-art equipment and advanced technology, CD BioSciences offers customer all over the word services related to fields of centrosomal research. Our one-stop service program is your best assistant to accelerate you process of centrosomal research. Please feel free to contact us and get started with our high-quality services.
Our services are for research use only and not for any clinical use.
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