CCP110 Rabbit Polyclonal Antibody (C-Terminus)

Cat. No.: CLAB-00230204

Product Size: 20 µL 100 µL Custom Size

Product Overview

Reactivity
Human, Monkey
Clonality
Polyclonal
Host Species
Rabbit
Conjugation
Unconjugated
Applications
IHC, IHC-P, WB

Target Information

Target Name
CCP110
UniProt No.
Gene ID
Alternative Names
CCP110; CP110; Centrosomal protein of 110 kDa; KIAA0419; Centrosomal protein CP110; Cep110
Function
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation. Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2.
Tissue Specificity
Highly expressed in testis. Detected at intermediate levels in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Store at -20 °C. Aliquot to avoid freeze/thaw cycles.

For Research Use Only. Not For Clinical Use.

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