Product Size
100 mg
25 mg
Custom Size
Product Overview
Description
DNA alkylating agent.
Target
DNA alkylating agent
Biological Description
DNA alkylating agent. Forms interstrand crosslinks in DNA preventing DNA replication and transcription. Inhibitor of glutathione reductase, lipoamide dehydrogenase and trypanothione reductase. Active in vivo.
Solubility Overview
Soluble in water to 25 mM, in ethanol to 100 mM and in DMSO to 100 mM.
Chemical Properties
Chemical Name
1,3-Bis(2-chloroethyl)-1-nitrosourea
Molecular Weight (Da)
214.05
Molecular Formula
C5H9Cl2N3O2
SMILES
C(CCl)NC(=O)N(CCCl)N=O
Storage & Handling
Storage Instructions
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
