Carmofur, Antimetabolite Agent

Cat. No.
CLIA-0130036
Product Size
5 g 1 g Custom Size

Product Overview

Description
Potent acid ceramidase inhibitor. Antimetabolite agent.
Purity
> 97%
Form
Solid
Biological Description
Potent acid ceramidase inhibitor (IC50 = 29 nM). Antimetabolite agent. cytostatic pyrimidine analogue derivative of fluorouracil (Asc 2387). Shows antitumor effects in vivo. Orally active.
Source
Synthetic
CAS Number
61422-45-5
Solubility Overview
Soluble in DMSO to 50 mM.

Chemical Properties

Chemical Name
5-Fluoro-N-hexyl-2,4-dioxopyrimidine-1-carboxamide
Molecular Weight (Da)
257.26
Molecular Formula
C11H16FN3O3
PubChem Identifier
SMILES
CCCCCCNC(=O)N1C=C(C(=O)NC1=O)F

Storage & Handling

Storage Instructions
Store at 4 °C. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

For Research Use Only. Not For Clinical Use.

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