Product Size
5 mg
25 mg
Custom Size
Product Overview
Description
Potent, irreversible proteasome inhibitor.
Alternative Names
KYPROLIS; PR-171; Proteolix
Solubility Overview
Soluble in DMSO to 100 mM and in ethanol to 25 mM.
Chemical Properties
Chemical Name
(αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]- L-phenylalaninamide
Molecular Weight (Da)
719.93
Molecular Formula
C40H57N5O7
SMILES
CC(C)C[C@@H](C(=O)[C@]1(CO1)C)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC3=CC=CC=C3)NC(=O)CN4CCOCC4
Storage & Handling
Storage Instructions
Shipped at room temperature. Store at -20 °C. Store under desiccating conditions.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
