Product Size
50 mg
5 mg
Custom Size
Product Overview
Description
Potent irreversible EGFR and HER2/ErbB2 tyrosine kinase inhibitor.
Alternative Names
CI-1033
Target
EGFR and HER2/ErbB2 tyrosine kinase
Solubility Overview
Soluble in DMSO to 100 mM.
Chemical Properties
Chemical Name
N-[4-(3-Chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide dihydrochloride
Molecular Weight (Da)
558.86
Molecular Formula
C24H25ClFN5O3.2HCl
SMILES
C=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4.Cl.Cl
Storage & Handling
Storage Instructions
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
