Butyrolactone I, ATP-competitive Cyclin-dependent Kinase (CDK) Inhibitor

Cat. No.
CLIA-0130039
Product Size
200 μg 50 μg Custom Size

Product Overview

Description
Cell permeable, selective, ATP-competitive cyclin-dependent kinase (CDK) inhibitor.
Purity
> 97%
Form
Solid
Target
ATP-competitive cyclin-dependent kinase (CDK)
Biological Description
Cell permeable, selective, ATP-competitive CDK inhibitor. Inhibits CDC2, CDK2, and CDK5. Inhibits the cell cycle at G1/S and G2/M. Apoptotic and antitumor activity.
Source
Synthetic
CAS Number
87414-49-1
Solubility Overview
Soluble in DMSO to 10 mM and in ethanol to 50 mM.

Chemical Properties

Chemical Name
Methyl (2S)-4-hydroxy-2-[[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]methyl]-3-(4-hydroxyphenyl)-5-oxofuran-2-carboxylate
Molecular Weight (Da)
424.50
Molecular Formula
C24H24O7
PubChem Identifier
SMILES
CC(=CCC1=C(C=CC(=C1)CC2(C(=C(C(=O)O2)O)C3=CC=C(C=C3)O)C(=O)OC)O)C

Storage & Handling

Storage Instructions
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

For Research Use Only. Not For Clinical Use.

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