BLOC1S2 Rabbit Polyclonal Antibody (aa14-40)

Cat. No.: CLAB-00230147

Product Size: 20 µL 100 µL Custom Size

Product Overview

Isotype
IgG
Reactivity
Human, Mouse
Clonality
Polyclonal
Host Species
Rabbit
Conjugation
FITC
Applications
ELISA, Flow Cyt, IHC, WB

Target Information

Target Name
BLOC1S2
UniProt No.
Gene ID
Alternative Names
BLOC1S2; Centrosome protein oncogene; Centrosome-associated protein; CEAP; RP11-316M21.4; BLOC-1 subunit 2; BLOS2; Centrosomal 10 kDa protein
Function
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles , such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. May play a role in cell proliferation.
Tissue Specificity
Isoform 1 and isoform 2 are widely expressed. Expressed in various malignant tumor tissues.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Short term: store at 4 °C. Long term: aliquot and store at -20 °C for up to 6 months. Avoid freeze-thaw cycles. Protect from light.

For Research Use Only. Not For Clinical Use.

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