BLOC1S2 Mouse Monoclonal Antibody

Cat. No.: CLAB-00230131

Product Size: 20 µL 100 µL Custom Size

Product Overview

Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Conjugation
Unconjugated
Applications
ELISA

Target Information

Target Name
BLOC1S2
UniProt No.
Gene ID
Alternative Names
BLOC1S2; Centrosome protein oncogene; Centrosome-associated protein; CEAP; RP11-316M21.4; BLOC-1 subunit 2; BLOS2; Centrosomal 10 kDa protein
Function
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles , such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. May play a role in cell proliferation.
Tissue Specificity
Isoform 1 and isoform 2 are widely expressed. Expressed in various malignant tumor tissues.

Shipping & Handling

Shipping
Shipped on dry ice.
Storage
Short term: store at 4 °C. Long term: store at -20 °C. Avoid freeze-thaw cycles.

For Research Use Only. Not For Clinical Use.

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