Product Size
250 mg
50 mg
Custom Size
Product Overview
Description
Angiotensin-converting enzyme (ACE) inhibitor. Prodrug.
Target
Angiotensin-converting enzyme (ACE)
Biological Description
Angiotensin-converting enzyme (ACE) inhibitor (IC50 = 0.27 nM). Prodrug. Orally active in vivo. Antihypertensive. Minimal ability to cross the blood-brain barrier.
Solubility Overview
Soluble in water to 25 mM, in ethanol to 100 mM and in DMSO to 100 mM.
Chemical Properties
Chemical Name
3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid hydrochloride
Molecular Weight (Da)
460.96
Molecular Formula
C24H28N2O5.HCl
SMILES
Cl.O=C(OCC)C(CCc1ccccc1)NC3CCc2ccccc2N(CC(=O)O)C3=O
Storage & Handling
Storage Instructions
Store at 4 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
