Product Overview
Target Information
Alternative Names
bccip; BCCIP_HUMAN; BCCIPalpha; BCCIPbeta; BRCA2 and CDKN1A interacting protein; BRCA2 and CDKN1A-interacting protein; BRCA2 and Cip1/p21 interacting protein; Cdk inhibitor p21 binding protein; P21 and CDK associated protein 1; P21- and CDK-associated protein 1; Protein TOK-1; Protein TOK1; TOK 1; TOK 1alpha; TOK 1beta; TOK1
Function
May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining.
Tissue Specificity
Expressed at high levels in testis and skeletal muscle and at lower levels in brain, heart, kidney, liver, lung, ovary, pancreas, placenta, and spleen.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage
Upon delivery aliquot and store at -20 °C or -80 °C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine). pH: 7.00.
Preservative
0.01% Thimerosal (merthiolate)