Astrin/Deepest Rabbit Polyclonal Antibody

Cat. No.: CLAB-00230047

Product Size: 20 µL 100 µL Custom Size

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Product Overview

Isotype

IgG

Reactivity

Human

Clonality

Polyclonal

Host Species

Rabbit

Conjugation

Unconjugated

Applications

IP, WB

Target Information

Target Name

SPAG5

UniProt No.

Q96R06

Gene ID

10615

Alternative Names

Astrin; Deepest; hMAP 126; hMAP126; MAP 126; MAP126; Mitotic spindle associated protein; Mitotic spindle associated protein p126; Mitotic spindle coiled coil related protein; Mitotic spindle-associated protein p126; SPAG 5; SPAG5; SPAG5_HUMAN; Sperm associated antigen 5; Sperm tail protein Spag 5; Sperm tail protein Spag5; Sperm-associated antigen 5

Function

Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin -kinastrin complex promotes stable microtubule-kinetochore attachments.

Tissue Specificity

Highly expressed in testis. Detected at low levels in placenta, liver, pancreas, thymus and colon.

Shipping & Handling

Shipping

Shipped on dry ice.

Storage

Store at 4 °C short term (1-2 weeks). Upon delivery aliquot. Store at -20 °C long term. Avoid freeze / thaw cycle.

Storage Buffer

Tris buffered saline, 0.1% BSA. pH: 6.8.

Preservative

0.09% Sodium Azide

For Research Use Only. Not For Clinical Use.