Product Size
50 mg
10 mg
Custom Size
Product Overview
Description
Cytochrome c caspase activator and apoptosis inducer.
Target
Cytochrome c caspase
Biological Description
Cell-permeable cytochrome c caspase activator. Promoting cytochrome-c dependent oligomerization of Apaf-1 into the mature apoptosome. Induces apoptosis in tumor cells (IC50 = ~4 µM).
Solubility Overview
Soluble in DMSO to 100 mM.
Chemical Properties
Chemical Name
1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione
Molecular Weight (Da)
306.15
Molecular Formula
C15H9Cl2NO2
SMILES
Clc1ccc(cc1Cl)CN3c2ccccc2C(=O)C3=O
Storage & Handling
Storage Instructions
Store at room temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
