Amsacrine, DNA Topoisomerase II Inhibitor

Cat. No.
CLIA-0130092
Product Size
50 mg 10 mg Custom Size

Product Overview

Description
DNA topoisomerase II inhibitor.
Purity
> 98%
Form
Solid
Target
DNA topoisomerase II
Biological Description
DNA topoisomerase II inhibitor. Antineoplastic agent. Intercalating planar polycyclic aromatic molecule which is active against a number of tumours in mice. Active in vivo.
Source
Synthetic
CAS Number
51264-14-3
Solubility Overview
Soluble in DMSO to 100 mM.

Chemical Properties

Chemical Name
N-[4-(9-Acridinylamino)-3-methoxyphenyl]methanesulfonamide
Molecular Weight (Da)
393.46
Molecular Formula
C21H19N3O3S
PubChem Identifier
SMILES
COC1=C(C=CC(=C1)NS(=O)(=O)C)NC2=C3C=CC=CC3=NC4=CC=CC=C42

Storage & Handling

Storage Instructions
Store at room temperature. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

For Research Use Only. Not For Clinical Use.

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