Amrinone, cAMP Phosphodiesterase Inhibitor

Cat. No.
CLIA-0130286
Product Size
1 g 250 mg Custom Size

Product Overview

Description
Selective cAMP phosphodiesterase inhibitor. Positive inotropic agent.
Purity
> 98%
Form
Solid
Target
cAMP phosphodiesterase
Biological Description
Selective cAMP phosphodiesterase inhibitor (IC50 values are 5 and 16 μM for 3A and 3B respectively). Positive inotropic agent. Shows anticonvulsive and vasodilatory effects in vivo.
Source
Synthetic
CAS Number
60719-84-8
Solubility Overview
Soluble in DMSO.

Chemical Properties

Chemical Name
3-Amino-5-pyridin-4-yl-1H-pyridin-2-one
Molecular Weight (Da)
187.20
Molecular Formula
C10H9N3O
PubChem Identifier
SMILES
C1=CN=CC=C1C2=CNC(=O)C(=C2)N

Storage & Handling

Storage Instructions
Store at 4 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

For Research Use Only. Not For Clinical Use.

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