Product Size
100 mg
25 mg
Custom Size
Product Overview
Description
Potent, competetive dihydrofolate reductase inhibitor.
Target
Dihydrofolate reductase
Biological Description
Potent, competitive dihydrofolate reductase inhibitor. Shows antineoplastic and immunosuppressive effects in vivo. Orally active.
Solubility Overview
Soluble in DMSO.
Chemical Properties
Chemical Name
2-[[4-[(2,4-Diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
Molecular Weight (Da)
440.41
Molecular Formula
C19H20N8O5
SMILES
C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N
Storage & Handling
Storage Instructions
Store at room temperature. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
