Product Size
100 mg
500 mg
Custom Size
Product Overview
Description
eNaC blocker.
Biological Description
Epithelial sodium channel (eNaC) blocker. At higher concentrations, blocks the Na+/H+ exchange pathway. Also blocks transient reception potential cation (TRPC6 and TRPP3) channels.
Solubility Overview
Soluble in water to 10 mM (with heating) and in DMSO to 100 mM.
Chemical Properties
Chemical Name
N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride
Molecular Weight (Da)
266.09
Molecular Formula
C6H8ClN7O.HCl
SMILES
Cl.Clc1nc(C(=O)NC(=N)N)c(N)nc1N
Storage & Handling
Storage Instructions
Store at room temperature. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
