Product Size
25 mg
5 mg
Custom Size
Product Overview
Description
Potent, selective and reversible protein arginine methyltransferase inhibitor.
Target
Protein arginine methyltransferase
Biological Description
Potent, selective and reversible protein arginine methyltransferase inhibitor (IC50 = 1.63 μM). ROS° scavenger with antioxidant effects (IC50 = 8.3 μM). Inhibits arginine in vitro without competing for the AdoMet binding site. Modulates nuclear receptor-regulated transcription in vivo. Cell-permeable.
Solubility Overview
Insoluble in EtOH; insoluble in DMSO; ≥ 19.1 mg/mL in H2O.
Chemical Properties
Chemical Name
7,7'-(Carbonyldiimino)bis[4-hydroxy2-naphthalenesulfonic acid] disodium salt
Molecular Weight (Da)
548.45
Molecular Formula
C21H14N2Na2O9S2
SMILES
C1=CC2=C(C=C(C=C2C=C1NC(=O)NC3=CC4=CC(=CC(=C4C=C3)O)S(=O)(=O)[O-])S(=O)(=O)[O-])O.[Na+].[Na+]
Storage & Handling
Storage Instructions
Store at -20 °C. It is important to note that this product is reported to be light sensitive. Store in the dark. Store under desiccating conditions.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
