Product Size
1 x 96 tests
Custom Size
Product Information
Reactivity
Mouse, Human (predicted: Rat)
Sample Type
Cell Lysate, Tissue Homogenate
Assay Type
Semi-quantitative
Detection Method
Colorimetric
Target Information
Function
IGF-1 leads to the activation of AKT3, which may play a role in regulating cell survival. Capable of phosphorylating several known proteins. Truncated isoform 2/PKB gamma 1 without the second serine phosphorylation site could still be stimulated but to a lesser extent.
Sequence Similarities
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily. Contains 1 AGC-kinase C-terminal domain. Contains 1 PH domain. Contains 1 protein kinase domain.
Alternative Names
AKT; AKT1; AKT1 kinase; AKT1m; AKT2; AKT2 kinase; Akt3; AKT3_HUMAN; CAKT; CWS6; DKFZp434N0250; HIHGHH; kinase Akt1; MGC99656; MPPH; Murine thymoma viral (v-akt) homolog 2; pan-akt; PKB; PKB ALPHA; PKB beta; PKB gamma; PKB-GAMMA; PKB/Akt; PKBALPHA; PKBB; PKBBETA; PKBG; PKBGAMMA; PRKBA; PRKBB; PRKBG; Protein kinase Akt 2; Protein kinase Akt-2; Protein kinase Akt-3; Protein kinase B; Protein kinase B alpha; Protein kinase B beta; Protein kinase B gamma; Proto oncogene c Akt; Proto-oncogene c-Akt; RAC; RAC ALPHA; RAC alpha serine/threonine protein kinase; RAC BETA; RAC beta serine/threonine protein kinase; RAC PK alpha; RAC PK beta; rac protein kinase alpha; rac protein kinase beta; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RAC-beta serine/threonine-protein kinase; RAC-gamma; RAC-gamma serine/threonine-protein kinase; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; RACALPHA; RACalpha serine/threonine kinase; RACBETA; RACgamma; RACgamma serine/threonine protein kinase; RACPKgamma; serine threonine protein kinase; STK 2; STK-2; STK2; thymoma viral proto oncogene; thymoma viral proto oncogene 1; V akt murine thymoma viral oncogene homolog 1; V akt murine thymoma viral oncogene homolog 2; V akt murine thymoma viral oncogene homolog 3; V akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma); V-AKT murine thymoma viral oncogene homolog 1; V-AKT murine thymoma viral oncogene homolog 2; V-AKT murine thymoma viral oncogene homolog 3; vakt murine thymoma viral oncogene homolog 1; vakt murine thymoma viral oncogene homolog 2; vakt murine thymoma viral oncogene homolog 3
Tissue Specificity
In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney.
Shipping & Handling
Shipping
Shipped on dry ice.
Storage Instructions
Store at 4 °C. Please refer to protocols.
