AG-18, EGF Receptor Kinase Inhibitor

Cat. No.
CLIA-0130053
Product Size
50 mg 25 mg Custom Size

Product Overview

Description
A broad spectrum protein tyrosine kinase inhibitor that inhibits epidermal growth factor receptor.
Purity
> 98%
Form
Solid
Alternative Names
Tyrphostin A23, Tyrphostin 23, RG-50810
Target
EGFR kinase
Biological Description
A broad spectrum protein tyrosine kinase inhibitor that inhibits epidermal growth factor receptor, GTPase activity of transducin, aldosterone secretion in response to Angiotensin II, and suppresses the activation of MAP kinases.
Source
Synthetic
CAS Number
118409-57-7
Solubility Overview
Soluble in ethanol to 100 mM and in DMSO to 100 mM.

Chemical Properties

Chemical Name
2-[(3,4-Dihydroxyphenyl)methylene]propanedinitrile
Molecular Weight (Da)
186.17
Molecular Formula
C10H6N2O2
PubChem Identifier
SMILES
C1=CC(=C(C=C1C=C(C#N)C#N)O)O

Storage & Handling

Storage Instructions
Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

For Research Use Only. Not For Clinical Use.

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