Product Size
50 mg
250 mg
Custom Size
Product Overview
Description
A potent and selective AKT1 inhibitor.
Biological Description
A potent and selective AKT1 inhibitor, Ki = 11 nM. Also inhibts PKA, CDK2, GSK3β and ERK2 (Ki values are 16, 46, 110, 260 nM respectively).
Solubility Overview
Soluble in DMSO to 50 mM.
Chemical Properties
Chemical Name
(2S)-1-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxy-3-phenylpropan-2-amine
Molecular Weight (Da)
358.44
Molecular Formula
C22H22N4O
SMILES
CC1=C2C=C(C=CC2=NN1)C3=CC(=CN=C3)OCC(CC4=CC=CC=C4)N
Storage & Handling
Storage Instructions
Shipped at room temperature. Store at -20 °C.
