6-Thioguanine, Antimetabolite

Cat. No.
CLIA-0130056
Product Size
1 g 500 mg Custom Size

Product Overview

Description
Antimetabolite. Guanine analog.
Purity
> 90%
Form
Solid
Target
Antimetabolite
Biological Description
Antimetabolite. Guanine analogue. Incorporates into mitochondrial DNA and induces DNA double-strand breaks. Antitumor, immunosuppressive and anti-inflammatory effects in vivo. Metabolite of Azathioprine. Orally active.
Source
Synthetic
CAS Number
154-42-7
Solubility Overview
Soluble in DMSO to 100mM.

Chemical Properties

Chemical Name
2-Amino-3,7-dihydropurine-6-thione
Molecular Weight (Da)
167.19
Molecular Formula
C5H5N5S
PubChem Identifier
SMILES
C1=NC2=C(N1)C(=S)N=C(N2)N

Storage & Handling

Storage Instructions
Store at room temperature. The product can be stored for up to 12 months.
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20 °C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

For Research Use Only. Not For Clinical Use.

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